Focus on diagnostics
We process the data
Cloud-based genetic diagnostics to accelerate laboratory workflows and enhance patient care.
One turnkey solution for all clinical NGS applications
Solution
The varvis® genomics platform is a complete solution for clinical diagnostics, supporting NGS raw data processing, genomics data management, and variant interpretation. Automated CNV and SNV analysis are clinically validated and completely integrated into the NGS workflow.
Bioinformatics
Automated. Validated. Fast.
varfeed® automates the processing of raw next-generation sequencing data from bcl, fastq or bam files. It performs all bioinformatics, including alignment and clinically validated CNV/SNV/Indel variant calling. All results are handed over to varvis® automatically. Pipeline validation is provided as a service – updates are included.
varvis® genomics software
Made for use in clinical diagnostics
varvis® is a clinical decision support system (CDS) and allows you to review, filter, and classify genetic variants. In addition, varvis® is your own comprehensive variant database. It supports the clinical decision-making process and is a registered CE-IVD device according to directive 98/79/EC.
Annotation
Always up to date
allexes® provides the data for variant annotation to varvis®. allexes® does not only deliver the most recent versions of public databases, but also provides access to aggregated genomic reference data from all our users compliant with HIPAA and EU regulations.
Key benefits
Automated QC
Important quality metrics are monitored automatically for every single NGS sample, but also across batches over time. Don't waste a moment on manual QC.
Push the button
Convenient filtering options such as inheritance filters and virtual panels allow you to filter from thousands of detected SNVs and CNVs. Within seconds.
80% savings
Our clinically validated CNV analysis provides significant time and cost savings compared to ligation based CNV detection methods.
Overnight express
No matter how many samples or how many sequencing runs you have: our fully automated process delivers results overnight. Guaranteed.
Use cases
NGS panels
Identify rare and causative SNV and CNV in a single validated process and replace conventional PCR-based methods.
Whole exome
sequencing
Do you need more than 15 minutes to interpret a whole exome? Accelerate WES interpretation by combining phenotype, family and inheritance information.
Liquid biopsy
Detect somatic variants with validated high sensitivity using state-of-the-art molecular barcoding technologies.
Carrier screening
Even the most complex scenarios are well covered in a single carrier screening filter in varvis® to solve your cases with just a few clicks.
See for yourself how varvis® can accelerate your laboratory workflows and increase your diagnostic yield.
Testimonials
University of Magdeburg
University of Leipzig
Synlab Zentrum für Humangenetik Mannheim
University of Göttingen
Gemeinschaftspraxis für Humangenetik & Genetische Labore Hamburg
Read more
Assurer la conformité : Les principales caractéristiques de notre logiciel de diagnostic génétique de pointe.
by Dr. Orianne Mazemondet, March 11, 2024
Le secteur du diagnostic génétique est en constante et rapide évolution et les laboratoires sont confrontés à des réglementations et des directives de plus en plus strictes pour assurer la précision, la fiabilité et la sécurité de leurs données.
Unveiling new insights into mitochondrial–nuclear interactions
by Dr. Roberta Trunzo, March 4, 2024
Exploring recent breakthroughs uncovering how nuclear DNA (nuDNA) variations impact mitochondrial DNA (mtDNA) dynamics, offers new insights into understanding human genetic diversity and its implications. Would you like to learn about mtDNA, the role of NGS in diagnosis of these disorders and what the varvis® software offers for mtDNA analysis?
The AWS S3 Denial of Wallet amplification attack
by Dr. Ben Liesfeld, Feb. 22, 2024
If you publicly host large data files on AWS S3 and pay for AWS transfer costs, you may be vulnerable to a “Denial of Wallet” amplification attack. Even if you are not hosting data publicly, you may be exposed to a malicious third-party attack or even a programming error, that can cause major costs within a short time frame.