Focus on diagnostics
We process the data

Cloud-based genetic diagnostics to accelerate laboratory workflows and enhance patient care.

One turnkey solution for all clinical NGS applications

NGS panels

Whole exome sequencing

Cancer diagnostics

Solution

The varvis® genomics platform is a complete solution for clinical diagnostics, supporting NGS raw data processing, genomics data management, and variant interpretation. Automated CNV and SNV analysis are clinically validated and completely integrated into the NGS workflow.

Bioinformatics

Automated. Validated. Fast.

varfeed® automates the processing of raw next-generation sequencing data from bcl, fastq or bam files. It performs all bioinformatics, including alignment and clinically validated CNV/SNV/Indel variant calling. All results are handed over to varvis® automatically. Pipeline validation is provided as a service – updates are included.

varvis® genomics software

Made for use in clinical diagnostics

varvis® is a clinical decision support system (CDS) and allows you to review, filter, and classify genetic variants. In addition, varvis® is your own comprehensive variant database. It supports the clinical decision-making process and is a registered CE-IVD device according to directive 98/79/EC.

Annotation

Always up to date

allexes™ provides the data for variant annotation to varvis®. allexes™ does not only deliver the most recent versions of public databases, but also provides access to aggregated genomic reference data from all our users compliant with HIPAA and EU regulations.

Key benefits

 
Automated QC

Important quality metrics are monitored automatically for every single NGS sample, but also across batches over time. Don't waste a moment on manual QC.

 
Push the button

Convenient filtering options such as inheritance filters and virtual panels allow you to filter from thousands of detected SNVs and CNVs. Within seconds.

 
80% savings

Our clinically validated CNV analysis provides significant time and cost savings compared to ligation based CNV detection methods.

  
Overnight express

No matter how many samples or how many sequencing runs you have: our fully automated process delivers results overnight. Guaranteed.

Use cases

NGS panels

Identify rare and causative SNV and CNV in a single validated process and replace conventional PCR-based methods.

Whole exome sequencing

Do you need more than 15 minutes to interpret a whole exome? Accelerate WES interpretation by combining phenotype, family and inheritance information.

Cancer diagnostics

Detect somatic variants with validated high sensitivity using state-of-the-art molecular barcoding technologies.

See for yourself how varvis® can accelerate your laboratory workflows and increase your diagnostic yield.

Let's schedule a demo!

Testimonials

Read more

Watch now: Diagnosing intellectual disability using exome analysis — you can do it!

by Yvonne Kasmann, October 18, 2020

During our corporate satellite at the Jornada AEGH 2020 we talked with our clinical expert, Prof. Rami Abou Jamra (University of Leipzig Medical Center) about why adequate and efficient exome analysis is the method of choice when diagnosing intellectual disabilities.

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RefSeq Select — a standardized algorithm to select your preferred RefSeq transcript

by Ben Liesfeld, October 2, 2020

Which transcript should I use to report a genomic variant? This is a frequent question from clinical geneticists now that Whole Exome Sequencing, which targets all known genes, has become widely available in clinical diagnostics.

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High-sensitivity solutions for liquid biopsy from NGS
 

by Ben Liesfeld, August 14, 2020

The varvis® software supports various technologies that allow to use NGS for tumor diagnostics or liquid biopsy applications. This enables our users to detect genomic variants at very low-allele frequencies while monitoring a relatively large genomic region.

Read more

Find more interesting articles in our blog

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