Revolutionizing clinical diagnostics with long-read sequencing using the varvis® software
An IVDR Class C certified platform
for secondary & tertiary analysis of long-read data.
Stop file juggling and switching between platforms. Say goodbye to guessing complex variants and manual counting of tandem repeats. With the varvis® software, an all-in-one IVDR certified solution, you can now analyze long-read data with confidence.
How it works
From raw data to actionable insights –
the varvis® platform facilitates and simplifies the analysis of complex long-read sequencing data.
Unlock insights from complex genomes
Enabling the detection of complex genetic variation and variant phasing to deliver actionable insights from long-read data — driving accurate and comprehensive clinical diagnostics.
Key analytical capabilities
Automated repeat expansion analysis
Detect pathogenic short tandem repeat (STR) expansions with a single click. No more manual counting of repeat expansions!
All variant details at a glance
Still referring to manuals to verify pathogenic ranges? Visualize pathogenic ranges and STR counts, and filter for the most relevant phenotype associations in one go using a clinician-friendly interface tailored for diagnostics.
Structural variant detection with precision
Detect breakpoints accurately and visualize complex rearrangements across the genome.
Why choose the varvis® software?
The varvis® software is a CE-IVD certified software solution for both short- and long-read sequencing analysis. Designed specifically for clinical diagnostics, the varvis® software automates IT, data processing, and quality control, allowing you to focus on delivering accurate and timely insights for patient care. With proven analytical performance, the platform ensures high-confidence results for genomic data, from SNVs to tandem repeats and complex structural variants (SVs). Whether you are working with whole genomes or targeting difficult regions, the varvis® software provides an easy and effective solution to aid your clinical decisions, making it your reliable tool in precision medicine.
Short and long-read
data analysis
Analyze both data types side by side in one unified platform - no need for multiple tools.
One-for-all sequencing
From challenging dark regions to whole genome, support any use case - at scale.
All-In-one
Valuable reference data for STRs and SVs to enhance and accelerate data interpretation (gnomAD-SV, DECIPHER, DGV and STRchive).
Trust your results
From SNV and CNV analysis, to STRs and complex re-arrangements, detect and classify variants with proven analytical performance.
Truly Hands-Free operation
Automated IT, data processing and quality control - no manual setup needed.
Certified
CE-IVD certified to meet regulatory standards and support patient diagnostics.
Long read sequencing is ready for clinical diagnostics!
Unlock the full potential of long-read sequencing. Elevate your analysis and uncover deeper insights from your genetic data with the varvis® software.
Read more
Can long-read sequencing replace array diagnostics in clinical routine?
by Dr. Ben Liesfeld, June 18, 2026
This white paper highlights how long-read sequencing is emerging as a strong alternative to array-based diagnostics in clinical genomics. It also explains how combining structural variant (SV) calling with coverage-based CNV analysis enables comprehensive detection across variant types, and how the varvis® platform brings these capabilities together in a unified long-read workflow.
Huntington’s disease: from understanding repeat instability to editing the genetic code
by Dr. Roberta Trunzo, April 14, 2026
Huntington’s disease (HD) has long been known as a genetic disorder caused by CAG repeat expansions in the HTT gene. Yet for decades, one key question remained unanswered: Why does the mutation remain silent for years, only to trigger neurodegeneration later in life? Recent discoveries have reshaped our understanding — and, for the first time, offered a way to intervene at the genetic level.
The future of diagnostics is long — and it’s already here.
by Dr. Roberta Trunzo, October 29, 2025
Long-read sequencing is moving from research into routine clinical use. Unlike traditional short-read methods, long reads reveal complex structural variants, repeat expansions, and previously inaccessible regions of the genome — facilitating far more diagnostic insight. In this blog article, Dr. Roberta Trunzo explains how the varvis® software bridges this transition, integrating short- and long-read data within a single certified workflow for precise, automated variant detection.